Genomic Medicine and Pharmacogenomics

Royal Pharmaceutical Society (RPS)

Pharmacogenomics | RPS (rpharms.com) The RPS is keen to educate and inform members on developments within Pharmacogenomics (PGx), to ensure that pharmacy is prepared to embrace the benefits of PGx for patients across all sectors of healthcare.

British Pharmacological Society and Royal College of Physicians

Personalised Prescribing – Using pharmacogenomics to improve patient outcomes, a report from the British Pharmacological Society and the Royal College of Physicians published 28 March 2022, calls for pharmacogenomic testing to be integrated fully, fairly and swiftly into the NHS.

Royal College of General Practitioners and British Society for Genetic Medicine

direct-to-consumer-genomic-testing-joint-position-statement-2025.pdf

The Royal College of General Practitioners (RCGP) and the British Society for Genetic Medicine (BSGM) recommend that health professionals should exercise caution when asked to offer, or provide, clinical expertise about the results of Direct to Consumer (DTC) genomic or genetic testing.

Consent and confidentiality in genomic medicine - new guidance for health professionals (rcpath.org)

Guidance on consent and confidentiality has been published by the College, the Royal College of Physicians and the British Society for Genetic Medicine to help healthcare professionals through the complex ethical issues that arise in genomic medicine.

NICE

Familial Hypercholesterolaemia:  Nice Guidelines

Familial breast cancer:  NICE Guidance

Guidance on CYP2C19 genotype testing to guide clopidogrel use after ischaemic stroke or transient ischaemic attack

UK Medical Eligibility Criteria for Contraceptive Use (UKMEC)

UKMEC includes guidance for breast conditions, family history of breast cancer, and carriers of known gene mutations: UK Medical Eligibility Criteria for Contraceptive Use

Medicines and Healthcare Products Regulatory Agency (MHRA)

The Yellow Card Biobank is a collaboration between the  Medicines and Healthcare products Regulatory Agency  (MHRA) and  Genomics England . Its goal is to improve understanding of how a patient’s genetic makeup may increase their risk of harm from side effects of medications. The Biobank is currently recruiting patients who have experienced side effects from specific medicines for a research project called the Yellow Card Biobank study.

Clinical Pharmacogenetics Implementation Consortium

The Clinical Pharmacogenetics Implementation Consortium is a reputable, internationally recognised, peer reviewed and evidence-based resource. However, be aware it is American and so the recommendations can sometimes be better aligned with FDA-licensed products.

Genomics in Pharmacy - Genomics Education Programme

NHS England Genomics Education Programme Genomics Education Programme - Genomics Education Programme (hee.nhs.uk)

NHS England’s Genomics Education Programme exists to deliver and advise on learning and development opportunities that prepare current and future NHS professionals to make the best use of genomics in their practice. Training resources include:

• GeNotes (Quick, concise information to help healthcare professionals make the right genomic decisions at each stage of a clinical pathway)
• Articles, Factsheets, videos, Podcasts
• Teaching and clinical resources
• Taught Courses, PGCert, PGDip, MSc

e-learning for health Genomics in the NHS – elearning for healthcare (e-lfh.org.uk)

The Genomics in the NHS programme is a collection of e-learning courses developed by NHS educational teams to support and educate healthcare professionals about genomic medicine and the benefit it will bring to patient care.

Royal College of General Practitioners (RCGP) Genomics toolkit Genomics toolkit: Introduction | RCGP Learning

The Genomics Toolkit has been developed in partnership with Health Education England Genomics Education Programme to support increasing understanding, raise awareness of Genomics Medicine and support primary care with increased knowledge of how genomics can contribute to improving patient care in a 'genomics era'. 

This toolkit is designed to be used by the entire clinical primary care team. It is a collection of resources that explain how Genomics Medicine can be incorporated in Primary Care, including training resources and audit suggestions, and providing links to relevant guidance and patient resources. The resources can be used as quick reference resources or as a package for CPD, to deliver awareness-raising and educational events, and in supporting trainees preparing for the MRCGP.

Future Learn The Genomics Era: The future of genomics in healthcare

An introduction to the growing role of genomics in healthcare, for patient diagnoses, treatment and disease prevention.

Centre for Pharmacy Postgraduate Education (CPPE) Genomics (cppe.ac.uk)

CPPE is a provider of educational solutions for the NHS pharmacy workforce across England to maximise its contribution to improving patient care. Genomic resources include:

• Links to medicines related education and tools for genomics
• Introduction to genomics in pharmacy e-learning package
• Genomics in pharmacy: an introduction to person centred consultations e-learning package

Medicines Learning Portal Medicines Learning Portal: Pharmacogenomics

This tutorial has been specially commissioned by NHS England is to support all pharmacists, pharmacy technicians and trainees working in primary and/or secondary care who currently have limited experience working with pharmacogenomic information.

Pharmacy and Genomics-informed Medicines Optimisation Webinar Recording

The NHSE Pharmacy Workforce Group for Genomics held a webinar for all pharmacy professionals providing NHS services on Tuesday 9^th September. Presenters included members of the NHS Genomic Medicine Service and NHSE National Genomics Education programme. The webinar provided an introductory overview for all pharmacy professionals on the area of genomics-informed medicines optimisation, including:

1. What is genomics?
2. What are the national priorities for genomics-informed medicines optimisation?
3. How does genomics affect medicines? (Pharmacogenomics, precision medicines and antimicrobial resistance)
4. Education opportunities for pharmacy professionals and introduction to the next webinar.

The webinar recording is now available on the pharmacy page for genomics education: 'Online courses, learning and resources' in the Link Bank.

Surrey Prescribing Advisory Database (PAD) Guidelines : Genomic Medicine (res-systems.net)

Genomic Medicine in Primary Care and Pharmacogenomics with Dr Debbie Hipps, Primary Care lead SE Genomic Medicine Service Alliance, and Sarah Flack, Primary Care Pharmacist, Surrey Heartlands ICB. The video is protected, please contact Surrey Training Hub team for password.

Getting to Grips with Genomics Series for Primary Care

• Getting to Grips with Genomics Part One: This webinar provides an introduction to genomics, including how and when to refer patients.

• Getting to Grips with Genomics Part Two: Lynch Syndrome Explained. Lynch Syndrome is an inherited condition which increases someone’s chances of developing cancer by 80% during their lifetime. 

ESR1 Breast ctDNA Testing Education Session - North Thames GMS : North Thames GMS

Cancer websites

MacMillan:  Cancer genetics booklet | Macmillan Cancer Support

Cancer research UK:  Family History and Inherited Cancer Genes

Ovacome:  Testing for the BRCA Gene Fault

Chemo-prevention for women with no history of breast cancer

Chemo-prevention:  NICE tamoxifen decision aid

Rare Disease websites

Genetic Alliance  is an umbrella organisation for 200 organisations, including Rare Disease UK, and Syndromes Without A Name, and support groups for individual rare diseases.  These provide information and support for patients and families affected by a genetic condition and are also a source of information and practical advice for healthcare professionals.

Unique  is a charity supporting and informing families with a rare chromosome disorder, and some single gene disorders. 

Unique also has a  list of guides  for healthcare professionals for individual chromosomal disorders (including deletions and duplications) in English and other languages.